Kaley Cuoco as Penny From CBS Comedy 'The Big Bang Theory'

On the CBS comedy The Big Bang Theory, Kaley Cuoco plays Penny, a bubbly young woman who lives across the hall from awkward nerds Leonard and Sheldon. Although their interests and occupations are baffling to her, Penny befriends her neighbors and grows very close to them. For a while, she even dated Leonard, and even after their break-up, she remains good friends with both him and Sheldon.